细胞生物学

厦门大学 · 大学MOOC · 共 89 节

细胞生物学是从事生物医学研究所必须掌握的课程之一。本课程为中英文双语教学，目的是让同学们尽快熟悉细胞生物学领域内的英文词汇，为掌握最新进展和提高自学能力奠定基础。欢迎对生命科学感兴趣，或者准备进一步深造，报考研究生，立志将来从事生命科学研究的同学选修本课程。

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课程目录

Introduction of Molecular cell biology
The objectives and development of cell biology 播放 Microscope and Cell theory 播放 Major events in cell biology 播放
Culturing and visualizing cells
Growing Cells in Culture 播放 Monoclonal antibodies 播放 Fluorescence Microscopy 播放 Flow cytometry 播放 Spinning Disk Confocal Microscopy 播放 FRAP and FRET 播放 RNA interference 播放
Biomembrane Structure
The structrures of the plasmic membrane 播放 The lipid bilayer: Composition and structural organization 播放 Forms of lipid molecules exist in water 播放 Lipids Movement in biomembrane 播放 Structure of Membrane Proteins 播放 Synthesis of Phospholipids and Intracellular Movement 播放
Transmembrane transport of Ions and small molecules
Overview of transmembrane transport 播放 Facilitated Transport of Glucose and Water 播放 ATP –powered pumps 播放 Na+/k+ pump 播放 Ca2+ pump 播放 K+ channel and the Resting membrane potencial 播放 Cotransport by Symporters and Antiporters 播放 Transcellular transport 播放
Cellular Energetics
Overview of aerobic oxidation 播放 Structure of Mitochondria 播放 Mitochondrial Oxidation of Fatty Acids Generates ATP 播放 The Electron Carriers and Electron Transport Chain 播放 The Electron Transport and Generation of the Proton-Motive Force 播放 Chemiosmotic theory and Endosymbiont hypothesis 播放 Harnessing the Proton-Motive Force to synthesize ATP 播放 Electron Transport and Reactive Oxygen Species (ROS) 播放
Moving Proteins into Membranes and Organelles
Targeting Proteins to and Across the ER Membrane 播放 Insertion of single-pass Proteins into the ER 播放 Insertion of Multipass Proteins into the ER 播放 Protein Glycosylation and Folding in the ER 播放 Formation of disulfide bonds in the ER 播放 Protein Quality Control in the ER 播放 Targeting of Proteins to Mitochondria 播放 Targeting of Peroxisomal Proteins 播放
Vesicular traffic,secretion and endocytosis
Molecular Mechanisms of Vesicle Budding and Fusion 播放 Early Stages of the Secretory Pathway 播放 Later Stages of the Secretory Pathway 播放 Receptor-Mediated Endocytosis 播放 Directing Membrane Proteins and Cytosolic Materials to the Lysosome 播放 The structure and functions of Lysosomes 播放
Signal transduction and G protein-coupled receptors
Brief Introduction of Cell Communication 播放 Signaling Molecules and Receptors 播放 G Proteins and G Protein-coupled Receptors (GPCR) 播放 GPCR Mediated Signaling pathways 播放
Signaling pathways that control gene activity
Outlines of Signaling pathways that control  gene activity 播放 Phosphoinositide Signaling Pathways 播放 TGF-b Receptors and TGFb Signaling Pathways 播放 Signaling Pathways controlled by Ubiquitination 播放 The Ras/MAPK and JAK/STAT signaling pathway 播放
Cell organization and movement I: Microfilaments
Actin Filaments 播放 Actin Filaments 播放 Dynamic Assembly of Actin Filaments 播放 Actin-Based Cellular Structures 播放 Myosins and Myosin-Powered Movements 播放
Cell organization and movement II: Microtubules and intermediate filament
第一单元 Microtubule Structure and Organization 播放 第二单元 Microtubule Dynamics 播放 第三单元 Regulation of Microtubule Structure and Dynamics 播放 第四单元 Kinesins & Dyneins: Microtubule-Based Motor Proteins 播放 第五单元 Cilia & Flagella: Microtubule-Based Surface Structures 播放 第六单元 Mitotic Spindle 播放 第七单元 Intermediate Filaments 播放 第八单元 Coordination and Cooperation Between Cytoskeletal Elements 播放
Nucleus, chromatin and chromosomes
第一单元 Unit 1, Nuclear Envelope (NE), Nuclear Pore Complex (NPC) & Nuclear Transport 播放 第二单元 Unit 2, Structural Organization of Eukaryotic Chromosomes 播放 第三单元 Unit 3, Morphology and Functional Elements of Eukaryotic Chromosomes 播放 第四单元 Unit 4, Nucleolus 播放
The Eukaryotic Cell Cycle
第一单元 Unit 1, Overview of the Cell Cycle and Its Control 播放 第二单元 Unit 2, Model Organisms and Methods to Study the Cell Cycle 播放 第三单元 Unit 3, CDK and Its Discovery 播放 第四单元 Unit 4, Regulation of CDK Activity 播放 第五单元 Unit 5, Commitment to the Cell Cycle and DNA Replication 播放 第六单元 Unit 6, Entry into Mitosis and Completion of Mitosis 播放 第七单元 Unit 7, Surveillance Mechanisms in Cell Cycle Regulation 播放 第八单元 Unit 8, Meiosis: A Special Type of Cell Division 播放
Integrating cells into tissues
An Overview on Cell-Cell and Cell-Matrix Adhesion 播放 Type of Cell Junctions and Anchoring Junctions 播放 Tight junctions and Gap junctions 播放 ECMs of The Basal Lamina 播放 ECMs of Connective tissue 播放
Stem cells, cell asymmetry and cell death
Early metazoan developmnt and embryonic stem cells 播放 Stem Cells and Niches in Multicellular Organisms 播放 Mechanisms of cell polarity and asymmetric cell division 播放 Cell death and its regulation 播放

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